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 Full Title Evaluating the potential of zooprophylaxis as a malaria control strategy in Tanzania: do livestock influence malaria mosquito survival, reproduction and transmission potential?

 Short Title

 Project Leader Issa Lyimo 
 Description The overall goal of this project is to evaluate the impact of livestock and other domestic animals on mosquito life history traits that influence their ability to sustain malaria transmission: survival, reproduction, and biting rate.

The three main objectives are:
1. To experimentally investigate the effect of vertebrate host choice (humans, livestock and domestic animals) by the malaria vectors An. gambiae s. s. and An. arabiensis on their survival and reproduction.

2. To test whether malaria exposure risk, as measured by mosquito vector abundance and infection rate, is lower in households who keep livestock than in those who do not.

3. To develop mathematical models based on the above data to identify if there are realistic scenarios in which malaria transmission within the Kilombero Valley of Tanzania could be reduced by a zooprophylaxis strategy, and predict how expected shifts in livestock availability under future land use.
 Collaborators Heather Ferguson                    University of Glasgow

Valeriana Mayagaya                 Ifakara Health Institute (IHI)

Matthew Alexander                  Ifakara Health Institute (IHI)

Gerry Killeen                           Ifakara Health Institute (IHI)

Gamba Nkwengulila                  University of Dar es Salaam       

 Source of funding Biotechnology and Biological Sciences Research Council (BBSRC UK)

 Start Date January 2006                        End Date     December 2010